Pro-Inflammatory wnt5a and Anti-Inflammatory sFRP5 Are Differentially Regulated by Nutritional Factors in Obese Human Subjects
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Pro-Inflammatory wnt5a and Anti-Inflammatory sFRP5 Are Differentially Regulated by Nutritional Factors in Obese Human Subjects
BACKGROUND Obesity is associated with macrophage infiltration of adipose tissue. These inflammatory cells affect adipocytes not only by classical cytokines but also by the secreted glycopeptide wnt5a. Healthy adipocytes are able to release the wnt5a inhibitor sFRP5. This protective effect, however, was found to be diminished in obesity. The aim of the present study was to examine (1) whether ob...
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متن کامل
probiotic yogurt affects pro- and anti-inflammatory factors in patients with inflammatory bowel disease
inflammatory bowel disease (ibd) is an irregular response of immune system accompanied with different inflammatory manifestations including alterations in cytokines. probiotics are non-pathogenic organisms with probable effects in various conditions such as inflammation. the present study hypothesized whether oral intake of bifidobacterium and lactobacillus in form of probiotic yogurt may repre...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0032437